产品货号：
Z20438
中文名称：
MEK3/MAP2K3抗体
英文名称：
Anti-MEK3/MAP2K3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MEK3/MAP2K3 Antibody |
| 指标别名 | MAP kinase kinase 3;MAP2K3;MAPK/ERK kinase 3;MAPKK 3;MAPKK3;MEK 3;MEK3;MKK3;PRKMK3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | MAP2K3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human MEK3(320-334aa MEHPFFTLHKTKKTD),identical to the related mouse and rat sequences. |
| 实际分子量 | 39KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Dual specificity mitogen-activated protein kinase kinase 3 is an enzyme that in humans is encoded by the MAP2K3 gene.The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family.This kinase is activated by mitogenic and environmental stress,and participates in the MAP kinase-mediated signaling cascade.It phosphorylates and thus activates MAPK14/p38-MAPK.This kinase can be activated by insulin,and is necessary for the expression of glucose transporter.Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase,which thus leads to the constitutive activation of MAPK14,and confers oncogenic transformation of primary cells.Rampoldi et al.(1997) localized the MAP2K3 gene to 17q11.2. |
| Uniprot ID | P46734 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | mitogen-activated protein kinase kinase 3 |
| 蛋白名全称 | Dual specificity mitogen-activated protein kinase kinase 3(MAP kinase kinase 3/MAPKK 3) |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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